Scientific Methodology & Review
FIG 1: Molecular differences between Tumor / NAT / Healthy tissue
Foundational Discovery: The Field Effect
Precision Selectivity
FIG 2: Ixgene Proprietary Target Selection Pipeline
Key References:
- Slaughter et al., "Field cancerization in oral squamous epithelium," 1953.
- Aran et al., "The landscape of normal-adjacent-to-tumor tissue," Nature Communications, 2017.
- Thomson et al., "Molecular signatures of the field effect," Science, 1998.